Journal Articles

72. H. Sallmon, A. Hatch, S.K. Murthy, B.D. Plouffe, and G. Hansmann. "Circulating Endothelial Cell Quantification by Microfluidics Chip in Pulmonary Arterial Hypertension" American Journal of Respiratory Cell and Molecular Biology 2017, 56, 680-682.
71. T. Narahari, D. Dendukuri, and S.K. Murthy. "Electrically-Actuated Valves for Woven Fabric Lateral Flow Devices" Analytical Chemistry 2017, 89, 4671-4679.
70. D.I. Walsh, D.S. Kong, S.K. Murthy, and P.A. Carr. "Enabling Microfluidics: From Clean Rooms to Makerspaces" Trends in Biotechnology 2017, 35, 383-392.
69. B.D. Plouffe and S.K. Murthy. "Fluorescence-Based Lateral Flow Assays for Rapid Oral Fluid Roadside Detection of Cannabis Use" Electrophoresis 2017, 38, 501-5016.
68. D. Bavli, E. Ezra, D. Kitsberg, M. Vosk-Artzi, S.K. Murthy, and Y. Nahmias. "One Step Antibody-Mediated Isolation and Patterning of Multiple Cell Types in Microfluidic Devices" Biomicrofluidics 2016, 10, 024112.
67. D.I. Walsh, S.K. Murthy, and A. Russom. “Ultra-High-Throughput Sample Preparation System for Lymphocyte Immunophenotyping Point-of-Care Diagnostics,” Journal of Laboratory Automation 2016, 21, 706-712. Cover Article.
66. C.H. do Prado, T. Narahari, F.H. Holland, H-N. Lee, S.K. Murthy, and H.C. Brenhouse. “Effects of Early Adolescent Environmental Enrichment on Cognitive Dysfunction, Prefrontal Cortex Development, and Inflammatory Cytokines After Early Life Stress,” Developmental Psychobiology 2016, 58, 482-491.
65. A.E. Adeniran-Catlett, L.D. Weinstock, E. Beguin, F.K. Bozal, A.T. Caraballo, and S.K.Murthy. “Accelerated Adipogenic Differentiation of hMSCs in a Microfluidic Shear Stimulation Platform,” Biotechnology Progress 2016, 32, 440-446.
64. L. Calvier, E. Legchenko, L. Grimm, H. Sallmon, A. Hatch, B. D. Plouffe, C. Schroeder, J. Bauersachs, S. K. Murthy, G. Hansmann. “Galectin-3 and Aldosterone as Potential Tandem Biomarkers in Pulmonary Arterial Hypertension,” Heart 2016, 102, 390-396. **Editor’s Choice.**
63. A.E. Adeniran-Catlett, E. Beguin, F.K. Bozal, and S.K.Murthy. “Suspension Based Differentiation of Adult Mesenchymal Stem Cells Toward Chondrogenic Lineage,” Connective Tissue Research 2016, 57, 466-475.
62. S. Hosic, S.K.Murthy, and A.N. Koppes. “Microfluidic Sample Preparation for Single Cell Analysis,” Analytical Chemistry 2016, 88, 354-380 (invited review article).
61. Y-C. Wang, J.W. Stein, C.L. Lynch, H.T. Tran, C-Y. Lee, R. Coleman, A. Hatch, V.G. Antontsev, H.S. Chy, C. O’Brien, S.K. Murthy, A.L. Laslett, S.E. Peterson, J.F. Loring. “Glycosyltransferase ST6GAL1 Regulates Pluripotency in Human Pluripotent Stem Cells,” Scientific Reports 2015, 5, 13317.
60. S. Kreimer, A.M. Belov, I. Ghiran, S.K. Murthy, D.A. Frank, and A.R. Ivanov. “Mass-Spectrometry-Based Molecular Characterization of Extracellular Vesicles: Lipidomics and Proteomics,” Journal of Proteome Research 2015, 14, 2367-2384.
59. D.I. Walsh, M.L. Lalli, J. M. Kassas, A.R. Asthagiri, and S.K. Murthy. “Cell Chemotaxis on Paper for Diagnostics,” Analytical Chemistry 2015, 87, 5505-5510.”
58. S. Li, B.D. Plouffe, A.M. Belov, S. Ray, X. Wang, S.K. Murthy, B.L. Karger, and A.R. Ivanov. “An Integrated Platform for Isolation, Processing and Proteomic Profiling of Rare Cells in Whole Blood.” Molecular and Cellular Proteomics 2015, 14, 1672-1683. Cover Article.
57. M.F. Diaz, N. Li, H.J. Lee, L. Adamo, S.M. Evans, H.E. Wiley, N. Arora, Y. Torisawa, D.A. Vickers, S.A. Morris, O. Naveiras, S.K. Murthy, D. E. Ingber, G.Q. Daley, G. Garcia-Cardena, P.L. Wenzel. “Biomechanical Forces Promote Blood Development through Prostglandin E2 and the cAMP-PKA Signaling Axis,” Journal of Experimental Medicine 2015, 212, 665-680.
56. T. Narahari, D. Dendukuri, and S.K. Murthy. “Tunable Electrophoretic Separations Using a Scalable, Fabric-Based Platform,” Analytical Chemistry 2015, 87, 2480-2487.
55. B.D. Plouffe, S.K. Murthy, and L.H. Lewis. “Fundamentals and Application of Magnetic Particles in Cell Isolation and Enrichment,” Reports on Progress in Physics 2015, 78, 016601 (invited review article).
54. R. Lin, A. Hatch, V.G. Antontsev, S.K. Murthy, and J.M. Melero-Martin, “Microfluidic Capture of Endothelial Colony-Forming Cells from Human Adult Peripheral Blood: Phenotypic and Functional Validation In Vivo,” Tissue Engineering Part C – Methods 2015, 21, 274-283.
53. J. Sun, G.L. Zhang, S. Li, A.R. Ivanov, D. Fenyo, F. Lisacek, S.K. Murthy, B.L. Karger, and V. Brusic. “Pathway Analysis and Transcriptomics Improve Protein Identification by Shotgun Proteomics from Samples Comprising Small Numbers of Cells: A Benchmarking Study.” BMC Genomics 2014, 15, S1.
52. B.D. Plouffe and S.K. Murthy. “Microfluidic Cell Separation: A Solved Problem?” Analytical Chemistry 2014, 86, 11481–11488 (invited Perspective Article).
51. B. Zhu, Y. Nahmias, M.L. Yarmush, and S.K. Murthy. “Microfluidic Isolation of CD34+ Skin Cells Enables Regeneration of Hair and Sebaceous Glands In Vivo.” Stem Cells Translational Medicine 2014, 3, 1354-1362. Cover Article.
50. D.I. Walsh, G.J. Sommer, U.Y. Schaff, P.S. Hahn, G.J. Jaffe, and S.K. Murthy, “Centrifugal Fluidic Immunoassay for Ocular Diagnostics with Enzymatically Hydrolyzed Fluorogenic Substrate,” Lab on a Chip 2014, 14, 2673-2680.
49. B. Zhang, C. Peticone, S.K. Murthy, and M. Radisic, “A Standalone Perfusion Platform for Drug Testing and Target Validation in Micro-Vessel Networks,” Biomicrofluidics 2013, 7, 044125.
48. N. Pestana, L. Mortensen, J. Runnels, D.A.L. Vickers, S.K. Murthy, C.P. Lin, and M. Niedre, “An Improved Prototype Diffuse Fluorescence Flow Cytometer for High Sensitivity Detection of Rare Circulating Cells In Vivo,” Journal of Biomedical Optics 2013, 18, 077002.
47. D.A.L. Vickers, E. J. Chory, M.C. Harless, and S.K. Murthy, “p38 Signaling and Receptor Recycling Events in a Microfluidic Endothelial Cell Adhesion Assay,” PLoS One 2013, 8, e65828.
46. B. Zhu, J. Smith, M.L. Yarmush, Y. Nahmias, B.J. Kirby, and S.K. Murthy, “Microfluidic Enrichment of Mouse Epidermal Stem Cells and Validation of Stem Cell Proliferation In Vitro,” Tissue Engineering Part C: Methods 2013, 19, 765-773.
45. N. Pestana, D. Walsh, A. Hatch, P. Hahn, G. J. Jaffe, S.K. Murthy, and M. Niedre, “A Dedicated Low-Cost Fluorescence Microfluidic Device Reader for Point-of-Care Ocular Diagnostics,” Journal of Medical Devices 2013, 7, 024501.
44. V. Tandon, B. Zhang, M. Radisic, and S.K. Murthy. “Generation of Tissue Constructs for Cardiovascular Regenerative Medicine: From Cell Procurement to Scaffold Design,” Biotechnology Advances 2013, 31, 722-735 (invited review article).
43. B. Zhu and S.K. Murthy. “Stem Cell Separation Technologies,” Current Opinion in Chemical Engineering 2013, 2, 3-7.
42. D.A.L. Vickers, E.J. Chory, and S.K. Murthy. “Separation of Two Phenotypically Similar Cell Types via a Single Common Marker in Microfluidic Channels,” Lab on a Chip 2012, 12, 3399-3407.
41. D.A.L. Vickers, M. Kulik, M. Hincapie, W.S. Hancock, S. Dalton, and S.K. Murthy. “Lectin-Functionalized Microchannels for Characterizing Pluripotent Cells and Early Differentiation,” Biomicrofluidics 2012, 6, 024122.
40. B. Zhang, J.V. Green, S.K. Murthy, and M. Radisic, “Label-Free Enrichment of Functional Cardiomyocytes Using Microfluidic Deterministic Lateral Flow Displacement,” PLoS One 2012, 7, e37619.
39. A. Hatch, D. M. Pesko, and S.K. Murthy, “Tag-Free Microfluidic Separation of Cells Against Multiple Markers,” Analytical Chemistry 2012, 84, 4618-4621.
38. E. Zettergren, D.A.L.Vickers, J. Runnels, S.K. Murthy, C.P. Lin, and M.Niedre, “An Instrument for Fluorescence Sensing of Circulating Cells with Diffuse Light in Mice In Vivo,” Journal of Biomedical Optics 2012, 17, 037001.
37. B.D. Plouffe, M. Mahalanabis, L.H. Lewis, C.M. Klapperich, and S.K. Murthy, “Clinically Relevant Microfluidic Magnetophoretic Isolation of Rare-Cell Populations for Diagnostic and Therapeutic Monitoring Applications,” Analytical Chemistry 2012, 84, 1336-1344. **Featured in Chemical & Engineering News (Click Here).**
36. G. Hansmann, B.D. Plouffe, A. Hatch, A. von Gise, H. Sallmon, R.T. Zamanian, and S.K. Murthy, “Design, Validation, and Clinical Application of an Endothelial Progenitor Cell Microfluidic Capture Chip in Patients with Cardiovascular Disease,” Journal of Molecular Medicine 2011, 89, 971-983.**Featured in Editorial Article (Click Here)**
35. B.D. Plouffe, D.K. Nagesha, R.S. DiPietro, S. Sridhar, D. Heiman, S.K. Murthy, and L.H. Lewis, “Thermomagnetic Determination of Fe3O4 Magnetic Nanoparticle Diameters for Biomedical Applications,” Journal of Magnetism and Magnetic Materials 2011, 323, 2310-2317.
34. B.D. Plouffe, L.H. Lewis, and S.K. Murthy. “Computational Design Optimization for Microfluidic Magnetophoresis,” Biomicrofluidics 2011, 5, 013413.
33. D.A.L. Vickers, M. Hincapie, W.S. Hancock, and S.K. Murthy. “Lectin-Mediated Microfluidic Capture and Release of Leukemic Lymphocytes from Whole Blood,” Biomedical Microdevices 2011, 13, 565-571.
32. J.V. Green, D. Sun, A. Hafezi-Moghadam, K. Lashkari, and S.K. Murthy. “Microfluidic Pillar Array Sandwich Immunofluorescence Assay for Ocular Diagnostics,” Biomedical Microdevices 2011, 13, 573-583.
31. A. Hatch, G. Hansmann, and S.K. Murthy. “Engineered Alginate Hydrogels for Effective Microfluidic Capture and Release of Endothelial Progenitor Cells from Whole Blood,” Langmuir 2011, 27, 4257-4264.
30. R.J. Camp, M. Lilies, J. Beale, N. Saedi, B. Flynn, E. Moore, S.K. Murthy, and J.W. Ruberti. “Molecular Mechanochemistry: Strain-Dependent Enzymatic Cleavage of Human Type I Collagen Monomer,” Journal of the American Chemical Society 2011, 133, 4073-4078.
29. D.A.L. Vickers and S.K. Murthy. “Receptor Expression Changes as a Basis for Endothelial Cell Identification Using Microfluidic Channels,” Lab on a Chip 2010, 10, 2380-2386.
28. L. Wang, S.K. Murthy, G.A. Barabino, and R.L. Carrier. “Synergic Effects of Crypt-like Topography and ECM Proteins on Intestinal Cell Behavior in Collagen Based Membranes,” Biomaterials 2010, 31, 7586-7598.
27. A.K.H. Achyuta, V.S. Polikov, A.J. White, H.G. Pryce Lewis, and S.K. Murthy. “Biocompatibility Assessment of Insulating Silicone Polymer Coatings Using an In Vitro Glial Scar Assay,” Macromolecular Bioscience 2010, 10, 872-880.
26. J.B. Leach, A.K.H. Achyuta, and S.K. Murthy.  “Bridging the Divide Between Neuroprosthetic Design, Tissue engineering, and Neurobiology,” Frontiers in Neuroengineering (invited review article; available online).
25. A.K.H. Achyuta, K.D. Stephens, H.G. Pryce Lewis, and S.K. Murthy. “Mitigation of Reactive Human Cell Adhesion on Poly(dimethylsiloxane) by Immobilized Trypsin,” Langmuir 2010, 26, 4160–4167.
24. J.V. Green, M. Radisic, and S.K. Murthy. “Deterministic Lateral Displacement as a Means to Enrich Large Cells for Tissue Engineering,” Analytical Chemistry 2009, 81, 9178-9182.
23. L. Wang, S.K. Murthy, W.H. Fowle, G.A. Barabino, and R.L. Carrier. “Influence of Micro-well Biomimetic Topography on Intestinal Epithelial Caco-2 Cell Phenotype,” Biomaterials 2009, 30, 6825-6834.
22. B.D. Plouffe, T. Kniazeva, J.E. Mayer, S.K. Murthy, and V.L. Sales. “Development of Microfluidics as Endothelial Progenitor Cell Capture Technology for Cardiovascular Tissue Engineering and Diagnostic Medicine,” FASEB Journal 2009, 23, 3309-3314. ** Featured in press release and local TV news media.**
21. J.V. Green and S.K. Murthy. “Microfluidic Enrichment of a Target Cell Type from a Heterogenous Suspension by Adhesion-Based Negative Selection,” Lab on a Chip 2009, 9, 2245-2248.
20. B.D. Plouffe, M.A. Brown, R.K. Iyer, M. Radisic, and S.K. Murthy. “Controlled Capture and Release of Cardiac Fibroblasts using Peptide-Functionalized Alginate Gels in Microfluidic Channels,” Lab on a Chip 2009, 9, 1507-1510. ** Featured as ‘Hot Article’ by journal.**
19. A.K.H. Achyuta, A.J. White, H.G. Pryce Lewis, and S.K. Murthy. “Incorporation of Linear Spacer Molecules in Vapor Deposited Silicone Polymer Thin Films,” Macromolecules 2009, 42, 1970-1978.
18. D.K. Nagesha, B.D. Plouffe, M. Phan, L.H. Lewis, S. Sridhar, and S.K. Murthy. “Functionalization-Induced Improvement in Magnetic Properties of Fe3O4 Nanoparticles for Biomedical Applications,” Journal of Applied Physics 2009, 105, 07B317.
17. J.V. Green, T. Kniazeva, M. Abedi, D. Sokhey, M.E. Taslim, and S.K. Murthy. “Effect of Channel Geometry on Cell Adhesion in Microfluidic Devices,” Lab on a Chip 2009, 9, 677-685.
16. A.K.H. Achyuta, R. Cieri, K. Unger, and S.K. Murthy. "Synergistic Effect of Immobilized Laminin and Nerve Growth Factor on PC12 Neurite Outgrowth," Biotechnology Progress 2009, 25, 227-234.
15. B.D. Plouffe, M. Radisic, and S.K. Murthy. "Microfluidic Depletion of Endothelial Cells, Smooth Muscle Cells, and Fibroblasts from Heterogeneous Suspensions," Lab on a Chip 2008, 8, 462-472.
14. B.D. Plouffe, D. N. Njoka, J. Harris, J. Liao, N.K. Horick, M. Radisic, and S.K. Murthy. “Peptide-Mediated Selective Adhesion of Smooth Muscle and Endothelial Cells in Microfluidic Shear Flow,” Langmuir 2007, 23, 5050-5055.
13. S.K. Murthy. “Nanoparticles in Modern Medicine: State of the Art and Future Challenges,” International Journal of Nanomedicine 2007, 2, 129-141.
12. W.S. O’Shaughnessy, S.K. Murthy, D.J. Edell, and K.K. Gleason. “Stable Biopassive Insulation Synthesized by Initiated Chemical Vapor Deposition of Poly(1,3,5-trivinyltrimethylcyclotrisiloxane),” Biomacromolecules 2007, 8, 2564-2570.
11. S.K. Murthy, P. Sethu, G. Vunjak-Novakovic, M. Toner, and M. Radisic. "Size-Based Microfluidic Enrichment of Neonatal Rat Cardiac Cell Populations," Biomedical Microdevices 2006, 8, 231-237.
10. M. Radisic, R.K. Iyer, and S.K. Murthy. “Micro- and Nano-technology in Cell Separation,” International Journal of Nanomedicine 2006, 1, 3-14 (review article; available for free download).
9. K.K.S. Lau, Y. Mao, H.G. Pryce Lewis, S.K. Murthy, B.D. Olsen, Leslie S. Loo, and K.K. Gleason. "Polymeric Nanocoatings by Hot-Wire Chemical Vapor Deposition (HWCVD)," Thin Solid Films, 2006, 501, 211-215.
8. A. Sin, S.K. Murthy, A. Revzin, R.G. Tompkins, and M. Toner. “Enrichment Using Antibody Coated Microfluidic Chambers in Shear Flow: Model Mixtures of Human Lymphocytes,” Biotechnology and Bioengineering 2005, 91, 816-826.
7. S.K. Murthy, A. Sin, R.G. Tompkins, and M. Toner. “Effect of Flow and Surface Conditions on Human Lymphocyte Isolation Using Microfluidic Chambers,” Langmuir 2004, 20, 11649-11655.
6. S.K. Murthy, B.D. Olsen, and K.K. Gleason. “Peptide Attachment to Vapor Deposited Polymeric Thin Films,” Langmuir 2004, 20, 4774-4776.
5. S.K. Murthy, B.D. Olsen, and K.K. Gleason. “Effect of Filament Temperature on the Chemical Vapor Deposition of Fluorocarbon-Organosilicon Copolymers,” Journal of Applied Polymer Science 2004, 91, 2176-2185.
4. J. Lin, S.K. Murthy, B.D. Olsen, K.K. Gleason, and A.M. Klibanov. “Making Thin Polymeric Materials Including Fabrics Microbicidal and also Water-Repellent,” Biotechnology Letters 2003, 25(19), 1661-1665.
3. K.K. S. Lau, S.K. Murthy, H.G. Pryce Lewis, J.A. Caulfield, and K.K. Gleason. “Fluorocarbon Dielectrics via Hot Filament Chemical Vapor Deposition,” Journal of Fluorine Chemistry 2003, 122, 93-96.
2. S.K. Murthy, B.D. Olsen, and K.K. Gleason. “Initiation of Cyclic Vinylmethylsiloxane Polymerization in a Hot-Filament Chemical Vapor Deposition Process,” Langmuir 2002, 18, 6424-6428.
1. S.K. Murthy and K.K. Gleason. “Fluorocarbon-Organosilicon Copolymer Synthesis by Hot Filament Chemical Vapor Deposition,” Macromolecules 2002, 35, 1967-1972.

 

Book Chapters

3. S.K. Murthy and M. Radisic. "Cell Adhesion and Detachment," in the Encyclopedia of Microfluidics and Nanofluidics, D. Li, Editor-in-Chief; Springer: 2008.
2. R.K. Iyer, B. Plouffe, S.K. Murthy, and M. Radisic. "Microreactors for Cardiac Tissue Engineering," in Micro- and Nano-engineering of the Cell Microenvironment: Technologies and Applications, A. Khademhosseini, J. Borenstein, S. Takayama, and M. Toner, Editors; Artech House Publishing: 2008.
1. S.K. Murthy, D.J. Edell, and K.K. Gleason. “Vapor Deposition of Biopassivation Coatings for Neuroprostheses,” in Neuroprosthetics: Theory and Practice, K.W. Horch and G. Dhillon, Editors; World Scientific Publishing: 2004.

 

Patents

4. S.K. Murthy, A. Hatch, and G. Hansmann. “Methods and Compositions for Highly Specific Capture and Release of Biological Materials,” International Patent Application No. PCT/US12/23859 filed February 3, 2012. Assignee: Northeastern University.
3. S.K. Murthy, L.H. Lewis, and B.D. Plouffe. “Methods and Compositions for Magnetophoretic Separation of Biological Materials,” International Application No. PCT/US12/23864 filed February 3, 2012. Assignee: Northeastern University.
2. S.K. Murthy, A.K.H. Achyuta, and H.G. Pryce Lewis. “Immobilization of Trypsin on Silicone Surfaces to Mitigate Reactive Human Cell Adhesion,” Provisional U.S. Patent Application filed August 2009. Assignee: Northeastern University.
1. K.K. Gleason and S.K. Murthy. “Fluorocarbon-Organosilicon Copolymers and Coatings Prepared by Hot-Filament Chemical Vapor Deposition,” U.S. Patent No. 6,887,578. Granted May 3, 2005. Assignee: Massachusetts Institute of Technology.

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